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AICDA Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, BvSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-77235AF350
Alexa Fluor 405
NBP1-77235AF405
Alexa Fluor 488
NBP1-77235AF488
Alexa Fluor 532
NBP1-77235AF532
Alexa Fluor 594
NBP1-77235AF594
Alexa Fluor 647
NBP1-77235AF647
Alexa Fluor 700
NBP1-77235AF700
Alexa Fluor 750
NBP1-77235AF750
Biotin
NBP1-77235B
DyLight 350
NBP1-77235UV
DyLight 405
NBP1-77235V
DyLight 488
NBP1-77235G
DyLight 594
NBP1-77235DL594
DyLight 650
NBP1-77235C
DyLight 680
NBP1-77235FR
DyLight 755
NBP1-77235IR
FITC
NBP1-77235F
HRP
NBP1-77235H
Janelia Fluor 549
NBP1-77235JF549
Janelia Fluor 646
NBP1-77235JF646
Unconjugated
NBP1-77235
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-77235
BSA Free
NBP1-77235
BSA Free
NBP1-77235-0.025mg
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AICDA Antibody [DyLight 550] Summary

Immunogen
Antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human AID. The immunogen is located within the last 50 amino acids of AID. Amino Acid Squence: EVDDLRDAFRTLGL
Predicted Species
Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AICDA
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AICDA Antibody [DyLight 550]

  • activation-induced cytidine deaminase
  • AICDA
  • AID
  • AIDCytidine aminohydrolase
  • Arp2
  • CDA2
  • HIGM2
  • HIGM2EC 3.5.4.5
  • integrated into Burkitt's lymphoma cell line Ramos

Background

Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol AICDA