Species: Hu, Mu, Pm
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF
Host: Rat Monoclonal
Species: Hu, Mu, Po, Bv
Applications: WB, ELISA, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
57379 |
| Alternate Names |
- activation-induced cytidine deaminase
- AIDCytidine aminohydrolase
- ARP2
- CDA2
- HIGM2EC 3.5.4.5
- integrated into Burkitt's lymphoma cell line Ramos
|
