Recombinant Human AGTR-2 Protein

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SDS-Page: Recombinant Human AGTR-2 Protein [H00000186-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, PA

Order Details

Recombinant Human AGTR-2 Protein Summary

Description
A recombinant protein with GST-tag at N-terminal corresponding to the amino acids 1-363 of Human AGTR2 full-length ORF

Source: Wheat Germ (in vitro)

Amino Acid Sequence:MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS

Details of Functionality
This protein is not active and should not be used for experiments requiring activity.
Protein/Peptide Type
Recombinant Protein
Gene
AGTR2
Purity
>80%, by SDS-PAGE

Applications/Dilutions

Application Notes
This protein has not been tested for any functionality. Product may contain endotoxins and is not suitable for use with live cells.
Reviewed Applications
Read 1 Review rated 4
using
H00000186-P01 in the following application:

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Purity
>80%, by SDS-PAGE

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human AGTR-2 Protein

  • AGTR2
  • AGTR-2
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for AGTR-2 Recombinant Protein (H00000186-P01) (0)

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Review for AGTR-2 Recombinant Protein (H00000186-P01) (1) 41

Average Rating: 4
(Based on 1 review)

Reviews using H00000186-P01:
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reviewed by:
Anonymous
06/30/2017
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Summary

CommentsA slight high molecular weight smear with HRP western blots, otherwise a well staining single band at an expected size

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Recent Reviews

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Anonymous
06/30/2017
Application:
Species:

Bioinformatics

Gene Symbol AGTR2
Entrez