AGTR-2 Antibody

Images

 
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-44282] - Analysis of anti-AGTR2 antibody with human adrenal.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-44282] - Analysis of anti-AGTR2 antibody with human adrenal.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-44282] - Analysis of anti-AGTR2 antibody with human uterus.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

AGTR-2 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from internal region of human AGTR2.
Specificity
This product is specific for AGTR2. Unless other species reactivities are specified there is no testing data currently available.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGTR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10 - 1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AGTR-2 Antibody

  • AGTR2
  • AGTR-2
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol AGTR2
Entrez