AGAP2 Antibody

Images

 
Western Blot: AGAP2 Antibody [NBP2-24498] - Analysis of AGAP2 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ...read more
Immunohistochemistry-Paraffin: AGAP2 Antibody [NBP2-24498] - Analysis human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, Eq, PmSpecies Glossary
Applications WB, ICC/IF, IHC, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

AGAP2 Antibody Summary

Immunogen
A portion of amino acids 450-500 of human AGAP2 was used as the immunogen.
Specificity
100% homologous to Human (isoform CRA_a).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGAP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence reported in scientific literature (PMID 34411567)
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Knockdown Validated reported in scientific literature (PMID 34411567)
  • Western Blot 1-3 ug/ml
Publications
Read Publications using
NBP2-24498 in the following applications:

  • 1 publication
  • KD
    1 publication
  • WB
    2 publications

Reactivity Notes

Opossum (86%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AGAP2 Antibody

  • AGAP-2
  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
  • arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
  • centaurin, gamma 1
  • centaurin-gamma-1
  • CENTG1
  • cnt-g1
  • FLJ16430
  • GGAP2
  • GTP-binding and GTPase activating protein 2
  • GTP-binding and GTPase-activating protein 2
  • KIAA0167
  • Phosphatidylinositol-3-kinase enhancer
  • phosphoinositide 3-kinase enhancer
  • PIKEArf GAP with GTP-binding protein-like, ANK repeat and PH domains 2

Background

AGAP2 (also known as centaurin-gamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidyl-inositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Publications for AGAP2 Antibody (NBP2-24498)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, KD, WB.


Filter By Application
ICC/IF
(1)
KD
(1)
WB
(2)
All Applications
Filter By Species
Human
(1)
Mouse
(1)
All Species

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for AGAP2 Antibody (NBP2-24498) (0)

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Secondary Antibodies

 

Isotype Controls

Additional AGAP2 Products

Array NBP2-24498

Research Areas for AGAP2 Antibody (NBP2-24498)

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Blogs on AGAP2

There are no specific blogs for AGAP2, but you can read our latest blog posts.
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Bioinformatics

Gene Symbol AGAP2