AGAP2 Products

Description

AGAP2 (also known as centaurin-gamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidyl-inositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.

Bioinformatics

Entrez	116986 Human 216439 Mouse 65218 Rat
Uniprot	AAH28020.1 Human AAM97540 Human NP_055585 Human NP_055585.1 Human Q99490 Human Q99490 Human
Product By Gene ID	116986
Alternate Names	AGAP-2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 centaurin, gamma 1 centaurin-gamma-1 Centaurin-gamma-1 CENTG1 cnt-g1 Cnt-g1 FLJ16430 GGAP2 GTP-binding and GTPase activating protein 2 GTP-binding and GTPase-activating protein 2 KIAA0167 Phosphatidylinositol-3-kinase enhancer phosphoinositide 3-kinase enhancer PIKEArf GAP with GTP-binding protein-like, ANK repeat and PH domains 2

Research Areas for AGAP2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis