AE Binding Protein 1/ACLP Antibody (590831) [Alexa Fluor™ Plus 405]

• Reactivity: Hu
• Clone: 590831
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

AE Binding Protein 1/ACLP Antibody (590831) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human ACLP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse ACLP is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AE Binding Protein 1/ACLP Antibody (590831) [Alexa Fluor™ Plus 405]

• ACLP
• ACLPadipocyte enhancer binding protein 1
• AE binding protein 1
• AE-binding protein 1adipocyte enhancer-binding protein 1
• AEBP1
• Aortic carboxypeptidase-like protein
• FLJ33612

Background

Aortic carboxypeptidase-like protein (ACLP), also known as adipocyte enhancer binding protein (AEBP1), is a 175 kDa molecule that contains a discoidin-like domain (aa 383-540) and a peptidase-like domain (aa 560-942). It is expressed in proliferating adipocytes and represses the transcription of FABP4. ACLP promotes macrophage cholesterol retention, the formation of foam cells, and inflammatory responses. It is also an extracellular matrix-associated protein found in fibrotic tissues including vascular smooth muscle. An alternately spliced isoform lacks aa 1-457 and has an altered sequence at its N-terminus. Over aa 345-1158, human ACLP shares 88% aa sequence identity with mouse and rat ACLP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.