AE Binding Protein 1/ACLP Products

Description

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.

Bioinformatics

Entrez	165 Human
Uniprot	NP_001120 Human
Product By Gene ID	165
Alternate Names	ACLP Aortic carboxypeptidase-like protein AE-binding protein 1adipocyte enhancer-binding protein 1 ACLPadipocyte enhancer binding protein 1 FLJ33612 AE binding protein 1

Diseases related to AE Binding Protein 1/ACLP

Discover more about diseases related to AE Binding Protein 1/ACLP.

Inflammation
Neoplasms
Malignant Neoplasms
Gastroschisis
Atherosclerosis
Obesity
Hyperplasia
Diabetes Mellitus
Carcinogenesis
Crest Syndrome
Aneurysm
Intraepithelial Neoplasia
Meningeal Disorder
Malignant Tumor Of Colon
Glioma
Cutis Laxa
Fibrosis
Pituitary Diseases

Pathways for AE Binding Protein 1/ACLP

View related products by pathway and learn more about each of the pathways below.

Cholesterol Efflux
Cell Differentiation
Wound Healing
Cell Growth
Localization
Pathogenesis
Cholesterol Homeostasis
Transport
Vascular Smooth Muscle Cell Differentiation
Muscle Cell Differentiation
Mammary Gland Development
Cholesterol Transport
Mating
Smooth Muscle Cell Differentiation
Cell Proliferation
Gland Development
Reverse Cholesterol Transport
Osteoclast Differentiation
Gene Silencing
Aging

PTMs for AE Binding Protein 1/ACLP

Learn more about PTMs related to AE Binding Protein 1/ACLP.

Phosphorylation
Cleavage
Sumoylation
Reduction
Deacetylation
Methylation
Ubiquitination

Bioinformatics Tool for AE Binding Protein 1/ACLP

Discover related pathways, diseases and genes to AE Binding Protein 1/ACLP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.