ADNP Antibody

Images

 
Immunohistochemistry: ADNP Antibody [NB110-40556] - Sample: FFPE section of human breast adenocarcinoma. Antibody: Affinity purified rabbit anti-ADNP used at a dilution of 1:250. Detection: DAB staining using ...read more
Immunohistochemistry: ADNP Antibody [NB110-40556] - Sample: FFPE section of human metastatic bone marrow. Antibody: Affinity purified rabbit anti-ADNP used at a dilution of 1:250. Detection: DAB staining using ...read more

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

ADNP Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 1050 and the C-terminus (residue 1102) of human Activity-Dependent Neuroprotective Protein using the numbering given in entry NP_056154.1 (GeneID 23394)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADNP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:100-1:500
Positive Control
ADNP Lysate (NBL1-07346)
Publications
Read Publication using NB110-40556.

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Gorilla, Chimpanzee, White-tufted-ear marmoset, Crab-eating macaque, Small-eared galago andNorthern white-cheeked gibbon. Rat reactivity reported in scientific literature (PMID: 18571851)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ADNP Antibody

  • Activity-dependent neuroprotective protein
  • activity-dependent neuroprotector homeobox
  • activity-dependent neuroprotector
  • ADNP homeobox 1
  • ADNP
  • ADNP1
  • ADNP1KIAA0784activity-dependent neuroprotector homeobox protein

Background

The activity-dependent neuroprotective protein (hADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. hADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. hADNP is implicated in maintaining cell survival, perhaps through modulation of p53.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ADNP Antibody (NB110-40556)(1)

We have publications tested in 1 confirmed species: Rat.


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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADNP
Entrez
Uniprot