ADAM22 Antibody (498805) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 498805
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

ADAM22 Antibody (498805) [Alexa Fluor® 532] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human ADAM22
  Gly26-His528
  Accession # Q9P0K1
• Specificity: Detects human ADAM22 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human ADAM8, 9, 10, 12, 15, 19, 23, 32, or 33 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ADAM22 Antibody (498805) [Alexa Fluor® 532]

• ADAM 22
• ADAM metallopeptidase domain 22
• ADAM22
• MDC2
• metalloproteinase-disintegrin ADAM22-3
• metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
• MGC149832

Background

Human ADAM22 is a member of the ADAM (a disintegrin and metalloprotease domain) family of metalloproteases. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins. They have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, such as fertilization, muscle development, and neurogenesis. ADAM22 is highly expressed in the brain and may function as an integrin ligand in the brain. The amino acid sequence of human ADAM22 is 100%, 96% and 92% identical to that of chimpanzee, dog and mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.