ACTR2 [p Thr238, p Thr237] Antibody

• Reactivity: Hu, Mu, Rt, Ch
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

ACTR2 [p Thr238, p Thr237] Antibody Summary

• Description: Stable for at least 1 year at -20°C.
• Immunogen: Phospho-ACTR2 (Thr-237/Thr-238) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding threonine 237 and threonine 238 in human ACTR2. This peptide sequence is highly conserved in rat, mouse, chicken, and fish ACTR2 proteins. [UniProt# P61160]
• Modification: p Thr237, p Thr238
• Specificity: The antibody detects 44 and 32 kDa proteins corresponding to the molecular mass of ACTR2 on SDS-PAGE immunoblots of human A431 and Jurkat cells treated with Calyculin A. This reactivity is not observed after lambda phosphatase treatment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ACTR2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Western Blot 1:1000
• Theoretical MW: 44 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C.
• Buffer: PBS, 1 mg/ml BSA and 50% glycerol
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for ACTR2 [p Thr238, p Thr237] Antibody

• actin-related protein 2
• ACTR2
• ARP2 (actin-related protein 2, yeast) homolog
• ARP2 actin-related protein 2 homolog (yeast)
• ARP2Actin-like protein 2

Background

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACTR2