ACTH Antibody (AH26 + 57) [DyLight 755]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
AH26 + 57
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

Order Details

ACTH Antibody (AH26 + 57) [DyLight 755] Summary

Immunogen
Synthetic peptide corresponding to aa1-24 of human ACTH (AH26); N-terminal fragment of human ACTH conjugated to KLH (57)
Localization
Cytoplasmic
Marker
Pituitary Marker
Specificity
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
POMC
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Reactivity Notes

Expected to show broad species reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ACTH Antibody (AH26 + 57) [DyLight 755]

  • ACTH
  • adrenocorticotropic hormone
  • Adrenocorticotropin
  • alpha-melanocyte-stimulating hormone
  • alpha-MSH
  • beta-endorphin
  • beta-LPH
  • beta-melanocyte-stimulating hormone
  • beta-MSH
  • CLIP
  • Corticotropin
  • corticotropin-like intermediary peptide
  • corticotropin-lipotropin
  • gamma-LPH
  • gamma-MSH
  • lipotropin beta
  • lipotropin gamma
  • LPH
  • melanotropin alpha
  • melanotropin beta
  • melanotropin gamma
  • met-enkephalin
  • MSH
  • NPP
  • POC
  • pro-ACTH-endorphin
  • proopiomelanocortin preproprotein
  • proopiomelanocortin
  • pro-opiomelanocortin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ACTH Antibody (NBP2-34550IR) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34550AF350
Alexa Fluor 405 NBP2-34550AF405
Alexa Fluor 488 NBP2-34550AF488
Alexa Fluor 532 NBP2-34550AF532
Alexa Fluor 594 NBP2-34550AF594
Alexa Fluor 647 NBP2-34550AF647
Alexa Fluor 700 NBP2-34550AF700
Alexa Fluor 750 NBP2-34550AF750
Allophycocyanin NBP2-34550APC
Biotin NBP2-34550B
DyLight 350 NBP2-34550UV
DyLight 405 NBP2-34550V
DyLight 488 NBP2-34550G
DyLight 550 NBP2-34550R
DyLight 594 NBP2-34550DL594
DyLight 650 NBP2-34550C
DyLight 680 NBP2-34550FR
DyLight 755 NBP2-34550IR
FITC NBP2-34550F
HRP NBP2-34550H
Janelia Fluor 549 NBP2-34550JF549
Janelia Fluor 646 NBP2-34550JF646
PE NBP2-34550PE

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Bioinformatics Tool for ACTH Antibody (NBP2-34550IR)

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Contact Information

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Bioinformatics

Gene Symbol POMC
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