ACTH Antibody (2F6) [Janelia Fluor® 646]


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Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Janelia Fluor 646

Order Details

ACTH Antibody (2F6) [Janelia Fluor® 646] Summary

Synthetic peptide corresponding to aa1-24 of human ACTH
Cytoplasm and Secreted
Pituitary Marker
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).AIt also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH
IgG1 Kappa
Protein A purified
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  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein A purified


Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ACTH Antibody (2F6) [Janelia Fluor® 646]

  • ACTH
  • adrenocorticotropic hormone
  • Adrenocorticotropin
  • alpha-melanocyte-stimulating hormone
  • alpha-MSH
  • beta-endorphin
  • beta-LPH
  • beta-melanocyte-stimulating hormone
  • beta-MSH
  • CLIP
  • Corticotropin
  • corticotropin-like intermediary peptide
  • corticotropin-lipotropin
  • gamma-LPH
  • gamma-MSH
  • lipotropin beta
  • lipotropin gamma
  • LPH
  • melanotropin alpha
  • melanotropin beta
  • melanotropin gamma
  • met-enkephalin
  • MSH
  • NPP
  • POC
  • pro-ACTH-endorphin
  • proopiomelanocortin preproprotein
  • proopiomelanocortin
  • pro-opiomelanocortin


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34529AF350
Alexa Fluor 405 NBP2-34529AF405
Alexa Fluor 488 NBP2-34529AF488
Alexa Fluor 532 NBP2-34529AF532
Alexa Fluor 594 NBP2-34529AF594
Alexa Fluor 647 NBP2-34529AF647
Alexa Fluor 700 NBP2-34529AF700
Alexa Fluor 750 NBP2-34529AF750
Allophycocyanin NBP2-34529APC
Biotin NBP2-34529B
DyLight 350 NBP2-34529UV
DyLight 405 NBP2-34529V
DyLight 488 NBP2-34529G
DyLight 550 NBP2-34529R
DyLight 594 NBP2-34529DL594
DyLight 650 NBP2-34529C
DyLight 680 NBP2-34529FR
DyLight 755 NBP2-34529IR
FITC NBP2-34529F
HRP NBP2-34529H
Janelia Fluor 549 NBP2-34529JF549
Janelia Fluor 646 NBP2-34529JF646
PE NBP2-34529PE
PerCP NBP2-34529PCP

Additional ACTH Products

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Bioinformatics Tool for ACTH Antibody (NBP2-34529JF646)

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