Acetylcholinesterase/ACHE Antibody (684CT8.3.4)

Images

 
Western Blot: Acetylcholinesterase Antibody (684CT8.3.4) [NBP2-32061] - ACHE Antibody (C-term) western blot analysis in Raji, Jurkat, COS7, mouse NIH/3T3 cell line and mouse cerebellum, rat cerebellum tissue lysates ...read more
Western Blot: Acetylcholinesterase Antibody (684CT8.3.4) [NBP2-32061] - Analysis in Raji, Jurkat, COS7, Mouse NIH/3T3 cell line and Mouse cerebellum, Rat cerebellum tissue lysates (35ug/lane).

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, RbSpecies Glossary
Applications WB
Clone
684CT8.3.4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Acetylcholinesterase/ACHE Antibody (684CT8.3.4) Summary

Background
Acetylcholinesterase Antibody (684CT8.3.4) (C-term) - Protein Information
Function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.

Subunit structure: Interacts with PRIMA1. The interaction with PRIMA1 is required to anchor it to the basal lamina of cells and or...ganize into tetramers By similarity. Isoform H generates GPI-anchored dimers; disulfide linked. Isoform T generates multiple structures, ranging from monomers and dimers to collagen-tailed and hydrophobic-tailed forms, in which catalytic tetramers are associated with anchoring proteins that attach them to the basal lamina or to cell membranes. In the collagen-tailed forms, isoform T subunits are associated with a specific collagen, COLQ, which triggers the formation of isoform T tetramers, from monomers and dimers. Isoform R may be monomeric.

Polymorphism: Acetylcholinesterase is responsible for the Yt blood group system [MIM:112100]. The molecular basis of the Yt(a)=Yt1/Yt(b)=Yt2 blood group antigens is a single variation in position 353; His-353 corresponds to Yt(a) and the rare variant with Asn-353 to Yt(b).
Show More
Immunogen
This Acetylcholinesterase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-611 amino acids from the C-terminal region of human Acetylcholinesterase.
Localization
Cellular Location:
Cell junction, synapse. Secreted (By similarity). Cell membrane; Peripheral membrane protein (By similarity) Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side (By similarity).

Tissue Location:
Isoform H is highly expressed in erythrocytes.
Predicted Species
Rabbit (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ACHE
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000
Theoretical MW
67.796 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for Acetylcholinesterase/ACHE Antibody (684CT8.3.4)

  • acetylcholinesterase (Yt blood group)
  • Acetylcholinesterase
  • ACHE
  • apoptosis-related acetylcholinesterase
  • ARACHE
  • EC 3.1.1
  • EC 3.1.1.7
  • N-ACHE
  • Yt blood group
  • YT

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF9024
Species: Mu, Rt
Applications: WB, IHC
NBP1-30052
Species: Hu, Mu, Rt, Av, Ch, GP, Pm
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-WhMt
NBP2-24916
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
NBP2-13306
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-32108
Species: Hu, Rt
Applications: WB, ICC/IF
NBP2-45897
Species: Hu
Applications: WB, IHC
NBP2-13075
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, IHC-FrFl
NB300-109
Species: Hu, Mu, Rt, Dr, I, Ma
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-FrFl
NBP1-81838
Species: Hu, Mu
Applications: WB, IHC, IHC-P
MAB4375
Species: Hu, Mu, Rt
Applications: IHC
NBP1-89726
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-49118
Species: Hu
Applications: IHC, IHC-P
NBP1-85740
Species: Hu, Po
Applications: WB, ICC/IF, IHC, IHC-P
H00010908-M08
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
NBP1-05163
Species: Hu, Rt, Po, Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P

Publications for Acetylcholinesterase/ACHE Antibody (NBP2-32061) (0)

There are no publications for Acetylcholinesterase/ACHE Antibody (NBP2-32061).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Acetylcholinesterase/ACHE Antibody (NBP2-32061) (0)

There are no reviews for Acetylcholinesterase/ACHE Antibody (NBP2-32061). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Acetylcholinesterase/ACHE Antibody (NBP2-32061) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Acetylcholinesterase/ACHE Products

Bioinformatics Tool for Acetylcholinesterase/ACHE Antibody (NBP2-32061)

Discover related pathways, diseases and genes to Acetylcholinesterase/ACHE Antibody (NBP2-32061). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Acetylcholinesterase/ACHE Antibody (NBP2-32061)

Discover more about diseases related to Acetylcholinesterase/ACHE Antibody (NBP2-32061).
 

Pathways for Acetylcholinesterase/ACHE Antibody (NBP2-32061)

View related products by pathway.

PTMs for Acetylcholinesterase/ACHE Antibody (NBP2-32061)

Learn more about PTMs related to Acetylcholinesterase/ACHE Antibody (NBP2-32061).
 

Research Areas for Acetylcholinesterase/ACHE Antibody (NBP2-32061)

Find related products by research area.

Blogs on Acetylcholinesterase/ACHE

There are no specific blogs for Acetylcholinesterase/ACHE, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Acetylcholinesterase/ACHE Antibody (684CT8.3.4) and receive a gift card or discount.

Bioinformatics

Gene Symbol ACHE
Entrez
Uniprot