Acetylcholinesterase/ACHE Antibody (684CT8.3.4)


Western Blot: Acetylcholinesterase Antibody (684CT8.3.4) [NBP2-32061] - ACHE Antibody (C-term) western blot analysis in Raji, Jurkat, COS7, mouse NIH/3T3 cell line and mouse cerebellum, rat cerebellum tissue lysates more
Western Blot: Acetylcholinesterase Antibody (684CT8.3.4) [NBP2-32061] - Analysis in Raji, Jurkat, COS7, Mouse NIH/3T3 cell line and Mouse cerebellum, Rat cerebellum tissue lysates (35ug/lane).

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

Acetylcholinesterase/ACHE Antibody (684CT8.3.4) Summary

Acetylcholinesterase Antibody (684CT8.3.4) (C-term) - Protein Information
Function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.

Subunit structure: Interacts with PRIMA1. The interaction with PRIMA1 is required to anchor it to the basal lamina of cells and or...ganize into tetramers By similarity. Isoform H generates GPI-anchored dimers; disulfide linked. Isoform T generates multiple structures, ranging from monomers and dimers to collagen-tailed and hydrophobic-tailed forms, in which catalytic tetramers are associated with anchoring proteins that attach them to the basal lamina or to cell membranes. In the collagen-tailed forms, isoform T subunits are associated with a specific collagen, COLQ, which triggers the formation of isoform T tetramers, from monomers and dimers. Isoform R may be monomeric.

Polymorphism: Acetylcholinesterase is responsible for the Yt blood group system [MIM:112100]. The molecular basis of the Yt(a)=Yt1/Yt(b)=Yt2 blood group antigens is a single variation in position 353; His-353 corresponds to Yt(a) and the rare variant with Asn-353 to Yt(b).
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This Acetylcholinesterase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-611 amino acids from the C-terminal region of human Acetylcholinesterase.
Cellular Location:
Cell junction, synapse. Secreted (By similarity). Cell membrane; Peripheral membrane protein (By similarity) Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side (By similarity).

Tissue Location:
Isoform H is highly expressed in erythrocytes.
Predicted Species
Rabbit (100%), Bovine (100%)
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
67.796 kDa

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Alternate Names for Acetylcholinesterase/ACHE Antibody (684CT8.3.4)

  • acetylcholinesterase (Yt blood group)
  • acetylcholinesterase
  • ACHE
  • apoptosis-related acetylcholinesterase
  • EC 3.1.1
  • EC
  • N-ACHE
  • Yt blood group
  • YT


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol ACHE

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