ACD Antibody (1C11-1A7)

Western Blot: ACD Antibody (1C11-1A7) [H00065057-M01] - Analysis of ACD expression in transfected 293T cell line by ACD monoclonal antibody (M01), clone 1C11-1A7.Lane 1: ACD transfected lysate (Predicted MW: 57.7 KDa).Lane 2: Non-transfected lysate.

Immunoprecipitation: ACD Antibody (1C11-1A7) [H00065057-M01] - Analysis of ACD transfected lysate using anti-ACD monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with ACD MaxPab rabbit polyclonal antibody.

Sandwich ELISA: ACD Antibody (1C11-1A7) [H00065057-M01] - Detection limit for recombinant GST tagged ACD is 1 ng/ml as a capture antibody.

Product Discontinued

ACD Antibody (1C11-1A7) Summary

• Immunogen: ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPGRCQSDAAMRVNGPASRAPAGWTSGSLHTGPRAGRPRAQARGVRGRGLLLRPRPAKELPLPRKGGAWAPAGNPGPLHPLGVAVGMAGSGRLVLRPWIRELILGSETPSSPRAGQLLEVLQDAEAAVAGPSHAPDTSDVGATLLVSDGTHSVRCLVTREALDTSDWEEKEFGFRGTEGRLLLLQDCGVHVQVAEGGAPAEFYLQVDRFSLLPTEQPRLRVPGCNQDLDVQKKLYDCLEEHLSESTSSNAGLSLSQLLDEMREDQEHQGALVCLAESCLTLEGPCTAPPVTHWAASRCKATGEAVYTVPSSMLCISENDQLILSSLGPCQRTQGPELPPPDPALQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEFKEFVGLPCKNRPPFPRTGATRGAQEPCSVWEPPKRHRDGSAFQYEYEPPCTSLCARVQAARLPPQLMAWALHFLMDAQPGSEPTPM
• Specificity: ACD - adrenocortical dysplasia homolog (mouse) (1C11-1A7)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ACD
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunoprecipitation 1:10 - 1:500
  • Sandwich ELISA
  • Western Blot 1:100 - 1:2000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ACD Antibody (1C11-1A7)

• adrenocortical dysplasia homolog (mouse)
• Pip1
• PIP1Tint1
• POT1 and TIN2 organizing protein
• POT1 and TIN2-interacting protein
• Ptop
• PTOPTpp1
• TIN2 interacting protein 1
• TINT1adrenocortical dysplasia protein homolog
• TPP1

Background

ACD encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACD