ACAT2 Antibody (A00083.01)

Product Discontinued

ACAT2 Antibody (A00083.01) Summary

• Immunogen: N-terminal amino acids of human ACAT2 protein (BC000408).
• Localization: localizes to the endoplasmic reticulum of human intestinal cells.
• Specificity: Mouse Monoclonal to ACAT2 (AT2.G7)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Gene: ACAT2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1/2000 - 1/5000
  • Western Blot 1/1000
• Theoretical MW: 41 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  ACAT2 Overexpression Lysate

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ACAT2 Antibody (A00083.01)

• acetoacetyl Coenzyme A thiolase
• acetyl-CoA acetyltransferase 2
• acetyl-CoA acetyltransferase, cytosolic
• Acetyl-CoA transferase-like protein
• acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)
• acetyl-Coenzyme A acetyltransferase 2
• ACTL
• Cytosolic acetoacetyl-CoA thiolase
• EC 2.3.1
• EC 2.3.1.9

Background

Acyl-coenzyme A: cholesterol acyltransferase 2 (SOAT2/ACAT2) catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A. It is associated with lipoprotein particle secretion and thus plays an important role in the metabolism of triglyceride-rich lipoproteins like ApoB100. In humans, ACAT2 is primarily expressed in the small intestine, whereas in other mammals, the enzyme is expressed in the liver and the small intestine. Human ACAT2 has 522 amino acids with an estimated molecular weight of 60 kDa

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACAT2
• Entrez:
  • 39(Human)
• Uniprot:
  • Q9BWD1(Human)