Mouse Abeta 42 ELISA Kit (Colorimetric)

Standard Curve Reference.

Samples were spiked with high concentrations of Mouse Abeta 42, and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

• Reactivity: Mu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 3.13 - 200 pg/mL
• Sensitivity: 1.88 pg/mL

Mouse Abeta 42 ELISA Kit (Colorimetric) Summary

• Description: Assay Length: 3 h 30 min
• Specificity: This kit recognizes Mouse Abeta 42 in samples. No significant cross-reactivity or interference between Mouse Abeta 42 and analogues was observed
• Standard Curve Range: 3.13 - 200 pg/mL
• Sensitivity: 1.88 pg/mL
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 10
• Intra-Assay: CV% < 10
• Spike Recovery: 80 - 120%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: APP

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Mouse Abeta 42 ELISA Kit (Colorimetric)

• Amyloid beta 42
• Beta-amyloid protein 42

Background

Amyloid beta-protein (Abeta) is associated with neuronal injury and death in Alzheimer's disease. The most common isoforms are of Amyloid beta are Abeta40 and Abeta42.

The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.

Mutations in Amyloid Precursor Protein (APP) that are associated with early-onset Alzheimer's have been shown to specifically increase the relative production of the Abeta42 isoform. Abeta 42 is also more fibrillogenic and plays a bigger role in deneurogeneration. It is therefore more strongly associated with Alzheimer's disease than Abeta 40.

Abeta42 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

FAQs for Abeta 42 ELISA Kit (NBP3-50033). (Showing 1 - 1 of 1 FAQ).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: APP