Abeta 42 Products

Abeta 42 Antibody (12F4)
Abeta 42 Antibody (12F4)
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, IF
Host: Mouse Monoclonal


Amyloid beta-protein (Abeta) is associated with neuronal injury and death in Alzheimer's disease. The most common isoforms are of Amyloid beta are Abeta40 and Abeta42.

The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.

Mutations in Amyloid Precursor Protein (APP) that are associated with early-onset Alzheimer's have been shown to specifically increase the relative production of the Abeta42 isoform. Abeta 42 is also more fibrillogenic and plays a bigger role in deneurogeneration. It is therefore more strongly associated with Alzheimer's disease than Abeta 40.

Abeta42 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.


Entrez Human
Product By Gene ID 351
Alternate Names
  • Amyloid beta 42
  • Beta-amyloid protein 42

Research Areas for Abeta 42

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Cell Cycle and Replication
Neuronal Cell Markers

Bioinformatics Tool for Abeta 42

Discover related pathways, diseases and genes to Abeta 42. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related Abeta 42 Blog Posts

Check out the latest blog posts on Abeta 42.
Using Amyloid beta peptides in Alzheimer's Disease Immunization
Amyloid beta (AB) peptide has a central role in the neurodegeneration of Alzheimer's disease (AD). Immunization of AD transgenic mice with AB-42 peptide reduces both the spatial memory impairments and AD-like neuropathologic changes.Therapeutic im...    Read more.
Amyloid beta and Methionine Sulfoxide Related to Abeta 42 Antibody and Abeta 40 Antibody
By Eric NeeleyAlzheimer's disease is a devastating neurodegenerative illness characterized by the formation of plaques, tangles, and eventually synaptic loss. Amyloid beta (A beta ) is the processed form of the Amyloid precursor protein (APP), and whose...    Read more.
Read more Abeta 42 related blogs.