ABCG2/CD338 Antibody (BXP-34)

Product Discontinued

ABCG2/CD338 Antibody (BXP-34) Summary

• Immunogen: BCRP over-expressing cell line MCF 7 MR.
• Epitope: Internal epitope.
• Marker: Stem Cell Marker
• Specificity: This does not cross react with the human MDR 1, MRP 1, MRP 2,or MRP 5 gene products.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Gene: ABCG2
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
• Application Notes: This antibody does not work in Western blot. Optimal dilutions / concentrations should be determined by the end user.

Reactivity Notes

Cross-reacts with Human.Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Purity: Tissue culture supernatant

Alternate Names for ABCG2/CD338 Antibody (BXP-34)

• ABC transporter
• ABC15
• ABCG2
• ABCP
• ABCPMGC102821
• ATP-binding cassette sub-family G member 2
• ATP-binding cassette transporter G2
• ATP-binding cassette, sub-family G (WHITE), member 2
• BCRP
• BCRP1
• BCRPMRX
• BMDP
• Breast cancer resistance protein
• CD338 antigen
• CD338
• CDw338
• EST157481
• mitoxantrone resistance protein
• Mitoxantrone resistance-associated protein
• MXR
• MXRMXR1
• placenta specific MDR protein
• Placenta-specific ATP-binding cassette transporter

Background

Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABCG2
• Entrez:
  • 9429(Human)