ABCA5 Antibody

Product Discontinued

ABCA5 Antibody Summary

• Immunogen: Peptide with sequence DYSSETSEDDDSLKC corresponding to internal region according to NP_758424.1.
• Epitope: internal region
• Specificity: Reported variants represent identical protein: NP_061142.2 and NP_758424.1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ABCA5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:1000
• Application Notes: WB: Preliminary experiments in human brain (cerebellum, cerebral cortex) lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for ABCA5 Antibody

• ABC13
• ATP-binding cassette A5
• ATP-binding cassette sub-family A member 5
• ATP-binding cassette, sub-family A (ABC1), member 5
• DKFZp451F117
• DKFZp779N2435
• EC 3.6.3
• EC 3.6.3.25
• EC 3.6.3.41
• EST90625
• FLJ16381
• KIAA1888

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ABCA5 Antibody (NBP1-20865)(1)

Publication using NBP1-20865

• Petry F, Kotthaus A, Hirsch-Ernst KI. Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant. Biochem Biophys Res Commun 2003-01-10 [PMID: 12504089]

Bioinformatics

• Gene Symbol: ABCA5
• Entrez:
  • 23461(Human)
• Uniprot:
  • NP_758424.1(Human)