AATK/Serine/threonine-protein kinase LMTK1 Antibody (456006) [Alexa Fluor™ Plus 647]

• Clone: 456006
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

AATK/Serine/threonine-protein kinase LMTK1 Antibody (456006) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human AATK in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AATK/Serine/threonine-protein kinase LMTK1 Antibody (456006) [Alexa Fluor™ Plus 647]

• AATK
• AATYK
• AATYKp35-binding protein
• apoptosis-associated tyrosine kinaseCDK5-binding protein
• Brain apoptosis-associated tyrosine kinase
• EC 2.7.11
• KIAA0641p35BP
• Lemur tyrosine kinase 1
• LMR1
• LMR1EC 2.7.11.1
• LMTK1
• LMTK1AATYK1
• p35BP
• serine/threonine-protein kinase LMTK1

Background

Apoptosis-associated tyrosine kinase (AATK) is a 155 kDa membrane-associated intracellular protein that promotes neurite extension and neuronal differentiation. Low extracellular potassium levels induce AATK phosphorylation and apoptosis in cerebellar granule cells. AATK negatively regulates the Na-K-2Cl cotransporter by promoting its PP1-dependent dephosphorylation. The two alternate splice forms of AATK also contain the sequences included in this immunogen. Within this region, human AATK shares 63% aa sequence identity with mouse AATK.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.