53BP2 Antibody (3F8)

Western Blot: 53BP2 Antibody (3F8) [H00007159-M01] - TP53BP2 monoclonal antibody (M01), clone 3F8 Analysis of TP53BP2 expression in HepG2.

Immunohistochemistry-Paraffin: 53BP2 Antibody (3F8) [H00007159-M01] - Analysis of monoclonal antibody to TP53BP2 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml.

Sandwich ELISA: 53BP2 Antibody (3F8) [H00007159-M01] - Detection limit for recombinant GST tagged TP53BP2 is approximately 0.3ng/ml as a capture antibody.

Product Discontinued

53BP2 Antibody (3F8) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: TP53BP2 (AAH58918, 511 a.a. ~ 610 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYS
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TP53BP2
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for 53BP2 Antibody (3F8)

• apoptosis-stimulating protein of p53, 2
• ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2
• Bbp
• Bcl2-binding protein
• p53-binding protein 2
• p53BP2
• PPP1R13A
• Renal carcinoma antigen NY-REN-51
• tumor protein p53 binding protein, 2
• tumor protein p53-binding protein, 2
• Tumor suppressor p53-binding protein 2

Background

53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TP53BP2