5-HT2C Antibody (496214) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 496214
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

5-HT2C Antibody (496214) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human 5HT2C in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for 5-HT2C Antibody (496214) [Alexa Fluor™ Plus 647]

• 5-HT1C
• 5-HT-1C
• 5HT2C
• 5-HT2C
• 5-HT-2C
• 5-HT2C5-hydroxytryptamine receptor 1C
• 5-HTR2C
• 5-hydroxytryptamine (serotonin) receptor 2C
• 5-hydroxytryptamine receptor 2C
• HTR1C
• HTR2C
• serotonin 5-HT-2C receptor
• Serotonin Receptor 2C

Background

5HT2C is a 45 kDa 7TM receptor for serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5HT2C ligation regulates mood, appetite, and motivation. 5HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5HT2C can be generated by RNA editing. Human 5HT2C shares 89% aa sequence identity with mouse and rat 5HT2C.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.