MMP-9 Products

Description

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGF beta and proTNF alpha. MMP9 contributes to the invasion and metastasis of various human malignancies.

Bioinformatics

Entrez	17395 Mouse 403885 Canine 4318 Human 81687 Rat
Uniprot	AAH06093 Human AAM97934 Human P14780 Human
Product By Gene ID	4318
Alternate Names	92 kDa gelatinase 92 kDa type IV collagenase CLG4B EC 3.4.24 EC 3.4.24.35 Gelatinase B GELB macrophage gelatinase MANDP2 matrix metallopeptidase 9 matrix metalloproteinase 9 matrix metalloproteinase-9 MMP-9 type V collagenase

Research Areas for MMP-9

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cellular Markers
Extracellular Matrix
GPCR

Related MMP-9 Blog Posts

Check out the latest blog posts on MMP-9.

Cytokeratin 18 - A Intermediate Filament Cyotskeletal Component Keratins, also called cytokeratins, are a family of filamentous structural proteins that form the intermediate filaments within epithelial cells. Keratins are differentially expressed depending on both the epithelial cell origin and degree of differen...    Read more.

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