Antibody suppliers

"Get the skinny" on Adiponectin & Leptin Antibodies

TAZ Antibody: The Devil is in the Details

WW domain-containing transcription regulator protein 1 also known as WWTR1 and TAZ, is a 44KDa protein that acts as a downstream regulatory target in the Hippo signaling pathway. This protein undergoes post-translational modification and becomes phosphorylated by LATS2 and STK3/MST2. TAZ in its phosphorylated state is functionally inactive and is retained in the cytoplasm. When TAZ is not phosphorylated it can be retained in the nucleus by a protein called MED15.

Simplifying IL6 Antibody Assays with ELISA kits

Interleukin 6 is a complex pleiotropic cytokine having both anti and pro-inflammatory effects. Alterations in expression contribute to many human diseases, and the IL6 antibody is widely used in the research areas of innate and adaptive immunity, autoimmune disorders; CAD (coronary artery disease); neurological disorders; cancer and inflammatory disease.

Adiponectin Antibody: Not Such a Weighty Issue

Adiponectin (also called AdipoQ and Acrp30) is a circulating cytokine primarily expressed in adipose tissue. A complex protein with a number of physiological roles, adiponectin antibody experiments have revealed multiple forms of the protein in circulation, including trimers, multioligomers and cleavage fragments. We at Novus Biologicals stock an extensive range of adiponectin antibodies, as well as recombinant proteins and ELISA adiponectin antibody kits.

The CD31/PECAM1 Antibody: Have it Your Way

Platelet Endothelial Cell Adhesion Molecule 1 (PECAM1) is a single-pass membrane receptor also known as CD31 (cluster of differentiation 31.) CD31 is expressed at high levels at endothelial cell junctions, and therefore the CD31 antibody is widely used as an endothelial marker, one use being to measure the progression of angiogenesis following recurrence of tumors.

A Multicolored Approach to CD4 Antibody Assays

Novus Biologicals offers the widest selection of conjugated CD4 antibody products, with a database that's continually expanding to take into account the latest developments. This includes CD4 antibodies conjugated to Dynomics and PE fluorescent dyes, for FACS analysis.

HSP Antibodies: Novel Therapies for MMP-induced Metastatic Breast Cancer

The matrix metalloproteinases are zinc-dependent protease enzymes which interact with a range of ECM (extracellular matrix) proteins, and are activated by proteolytic cleavage. We at Novus Biologicals offer a wide range of top quality MMP reagents, including MMP3, MMP7, MMP9, MMP13 and MMP2 specific antibodies.

NUP153 & 53BP1: A Novel DNA Repair Pathway

Mediating DNA damage is a crucial process, and one of the most important cellular guards against cancer. In response to DNA damage, sophisticated cellular machinery is recruited to repair the breaks, and if it fails, the cell is committed to death.

Cancer studies with ABCF2

ATP-binding cassette superfamily F2 (ABCF2) is a member of the ATP-binding cassette (ABC) transporter superfamily, and more specifically, a member of the GCN20 subfamily. Most members of this family are membrane proteins that transport various substrates across the cell membrane [1, 2].

BSP and Osteopontin Antibodies: A Case of SIBLING Rivalry

Bone and dentin are closely related tissues, formed when a type I collagen-rich extracellular matrix (ECM) is secreted from the osteoblasts or odontoblasts and subsequently mineralized. This process is tightly regulated by type I collagen plus a number of non-collagenous proteins, including members of the SIBLING (Small Integrin-Binding LIgand, N-linked Glycoprotein) family.

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