MST2/STK3 Products

Description

Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]

Bioinformatics

Entrez	6788 Human
Uniprot	NP_006272.2 Human
Product By Gene ID	6788
Alternate Names	EC 2.7.11 FLJ90748 KRS1 Mammalian STE20-like protein kinase 2 Mess1 MST2 MST-2 MST2EC 2.7.11.1 MST3 serine/threonine kinase 3 (STE20 homolog, yeast) serine/threonine kinase 3 (Ste20, yeast homolog) serine/threonine kinase 3 serine/threonine-protein kinase 3 Serine/threonine-protein kinase Krs-1 STE20-like kinase MST2 STK3

Research Areas for MST2/STK3

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Apoptosis