Antibody catalog

Ubiquitin is a small, highly conserved protein which plays an important role in protein breakdown, covalently bonding to proteins to mark them for proteolytic degradation in a process called ubiquitination. Ubiquitin also binds to inclusion bodies (accumulations of protein) in pathological conditions such as Parkinson’s and Alzheimer's disease.

We at Novus Biologicals are one of the leading antibody suppliers for cancer research. In a recent Notch antibody study, the Notch ligand Jagged 2 was found to promote the growth of metastatic lung cancer cells by inhibiting miR-200, which blocks epithelial-to-mesenchymal transition (EMT) – an early stage in metastasis which, if blocked, can prevent secondary tumour growth.

The Sox2 antibody is widely used in sensory, neuroscience and stem cell marker research. Recently, Sox2 antibody preparations identified the Sox2 protein as a marker for malignant neural gliomas. We at Novus Biologicals offer a wide variety of highly validated Sox2 antibodies.

Adiponectin (also called ADIPOQ) is a cytokine expressed exclusively in adipose tissue. It has a number of functions, regulating lipid metabolism, gluconeogenesis and the inflammatory response. Adiponectin antibody products are widely used in diabetes, obesity and lipid metabolism research. Obesity and Type 2 Diabetes are linked to an increased risk of breast cancer in women.

The enzymes of the Matrix Metalloproteinase (MMP) family assist in the degradation of the extracellular matrix, under both normal and pathological conditions. MMP antibodies have identified roles in a number of physiological processes, such as embryonic development and tissue remodelling. They also regulate enzyme cascades, expression of various proteins and the migration of both normal and malignant cells.

The V5 tag antibody identifies the V5 epitope tag, enabling proteins of interest to be analyzed and studied via ELISA, Western blot and other immunochemical methods. We at Novus Biologicals are one of the leading suppliers of epitope tag reagents, with an extensive range of V5 tag antibody products on our antibody database.

Novus' Lightning-Link HRP Antibody Labeling Kit (cat# 701-0000) has received some glowing product reviews and customer feedback lately. One satisfied customer wrote, "Fast, efficient, stable direct HRP conjugation - best reagent we have found..." Another reviewer wrote, "This conjugation kit worked beautifully [and] the procedure is so simple. Although we had some [initial] concerns, it worked very well."

Novus is launching a new Travel Grant offer for researchers who provide feedback on our antibodies.

For each complete product review that you submit, you will be entered into a drawing for a $500 travel grant! We will select a winner every 3 months - giving you 4 chances for you to win each year!  The winner will receive a $200 airline voucher and $300 towards registration for a scientific conference of your choice.

Survivin (BRIC5) is an inhibitor of apoptosis that also promotes cellular adaptation under stressful conditions and helps to regulate cell division. Recently, an antibody study by Dr. H Wang et al. at Brown University [PMID: 20826784] found that Survivin is acetylated at lysine residue 129, thereby affecting its subsequent subcellular localization.

Sorting Nexin Family Member 27 (SNX27) binds the cell membrane to regulate endocytic vesicular and protein trafficking. SNX27 has also been shown to play a key role in the endocytic recycling pathway, whereby internalized membrane proteins and lipids are degraded and recycled into the cell, in T lymphocytes. In their groundbreaking work on endocytic recycling pathways, Dr. F Maxfield and Dr. T McGraw showed that these pathways are essential for proper organelle maintenance and homeostatic regulation of molecules.