Home » IFITM3/Fragilis » Fragilis Antibodies » IFITM3/Fragilis Antibody (EPR5242)

IFITM3/Fragilis Antibody (EPR5242)

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-95757
    • Availability
      Product Discontinued

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IFITM3/Fragilis Antibody (EPR5242) Summary

Immunogen
A synthetic peptide corresponding to residues in human IFITM3 was used as an immunogen.
Clonality
Monoclonal
Host
Rabbit
Gene
IFITM3
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-250
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:250-500
  • Western Blot 1:1000-10000
Theoretical MW
15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 5
using
NBP1-95757 in the following applications:

Reactivity Notes

Species cross-reactivity is based on Western Blot analysis.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for IFITM3/Fragilis Antibody (EPR5242)

  • 1-8U
  • Fragilis
  • IFITM3
  • interferon induced transmembrane protein 3 (1-8U)
  • interferon-induced transmembrane protein 3
  • Interferon-inducible protein 1-8U
  • IP15
  • mil-1

Background

IFITM3 is a member of the IFITM family, which mediates cellular processes, including the homotypic cell adhesion functions of interferons (IFNs) (1). It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early steps of replication (2). High expression levels of IFITM3 have been found in gastric cancer cell and colorectal tumors (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IFITM3/Fragilis Antibody (NBP1-95757) (0)

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Review for IFITM3/Fragilis Antibody (NBP1-95757) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP1-95757:
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Western Blot IFITM3/Fragilis NBP1-95757
Enlarge 		5
reviewed by:
Miriam Dutra
 WB Human 01/28/2014
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Summary

ApplicationWestern Blot
Sample TestedHela whole cell lysate
SpeciesHuman
LotNBP1-95757

Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for IFITM3/Fragilis Antibody (NBP1-95757). (Showing 1 - 1 of 1 FAQ).

  1. Does your anti-IFITM3 antibody cross react with IFITM2 or it is specific only to IFITM3?
    • Our IFITM3 antibody with catalogue number NBP1-95757 has unfortunately not been tested for its cross-reactivity to other IFITMs. I checked through our other 14 antibodies to IFITM3, but was unable to find an alternative antibody that had been tested for reactivity against other IFITMs, I am sorry for any inconvenience. Since human IFITM3 and IFITM2 share a sequence homology of 90% it is highly likely that antibodies which recognise IFITM3 will also recognise IFITM2.

Secondary Antibodies

 

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Recent Reviews

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Western Blot IFITM3/Fragilis NBP1-95757
Enlarge
 Miriam Dutra
01/28/2014
Application: WB
Species: Human
read this review

Bioinformatics

Gene Symbol IFITM3
Entrez
Uniprot