ZWINT Antibody

Western Blot: ZWINT Antibody [H00011130-D01P] - Analysis of ZWINT expression in transfected 293T cell line by ZWINT polyclonal antibody.Lane 1: ZWINT transfected lysate(31.20 KDa).Lane 2: Non-transfected lysate.

Western Blot: ZWINT Antibody [H00011130-D01P] - analysis of ZWINT expression in transfected 293T cell line by ZWINT MaxPab rabbit polyclonal antibody. Lane 1: ZWINT transfected lysate (31.20 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

ZWINT Antibody Summary

• Immunogen: ZWINT (AAH20979.1, 1 a.a. - 277 a.a.) full-length human protein. MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDGVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
• Specificity: ZWINT - ZW10 interactor,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ZWINT
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ZWINT Antibody

• C20orf164
• chromosome 20 open reading frame 164
• dJ337O18.7
• zinc finger SWIM domain-containing protein 3
• zinc finger, SWIM domain containing 3
• zinc finger, SWIM-type containing 3

Background

This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ZWINT Antibody (H00011130-D01P)(1)

Publication using H00011130-D01P

• Matson DR, Demirel PB, Stukenberg PT, Burke DJ. A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint. FEBS J. 2012-03-16 [PMID: 22426531]

Bioinformatics

• Gene Symbol: ZWINT
• Entrez:
  • 11130(Human)
• Uniprot:
  • AAH20979.1(Human)