ZFAND5 Antibody (OTI5H8) [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI5H8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

ZFAND5 Antibody (OTI5H8) [DyLight 650] Summary

• Immunogen: Full length recombinant protein of human ZFAND5 (NP_005998) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ZFAND5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ZFAND5 Antibody (OTI5H8) [DyLight 650]

• Zinc finger A20 domain-containing protein 2
• Zinc finger protein 216ZA20D2
• zinc finger, AN1-type domain 5
• ZNF216A20 domain containing 2

Background

ZFAND5 inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apopt

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZFAND5