Ymer Antibody [Janelia Fluor® 669]

Product Discontinued

Ymer Antibody [Janelia Fluor® 669] Summary

• Immunogen: coiled-coil domain containing 50. (Uniprot# Q8IVM0)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCDC50
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Ymer Antibody [Janelia Fluor® 669]

• C3orf6deafness, autosomal dominant 44
• coiled-coil domain containing 50
• coiled-coil domain-containing protein 50
• DFNA44
• Protein Ymer
• Ymer

Background

Ymer encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCDC50