38.3 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4), 20% glycerol
>85%, by SDS-PAGE
Alternate Names for Recombinant Human YB1 His Protein
class II, Y box-binding protein I
DBPB CCAAT-binding transcription factor I subunit A
Enhancer factor I subunit A
NSEP1 Y-box-binding protein 1
nuclease-sensitive element-binding protein 1
Y box binding protein 1
YB1 DNA-binding protein B
YB-1 Y-box transcription factor
YBX1, also known as Y box binding protein 1, associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation. This protein is a potential drug target in cancer therapy. It helps the replication of adenovirus type 5, a commonly used vector in gene therapy. Thus, YBX1 can cause an "oncolytic" effect in YBX1 positive cancer cells treated with adenoviruses. Recombinant human YBX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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