Human WNT3 full-length ORF ( NP_110380.1, 1 a.a. - 355 a.a.) recombinant protein with GST-tag at N-terminal.
Details of Functionality
This protein is not active and should not be used for experiments requiring activity.
>80% by SDS-PAGE and Coomassie blue staining
This protein has not been tested for any functionality. Product may contain endotoxins and is not suitable for use with live cells. Use in functional reported in scientific literature (PMID 26108805)
66 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using H00007473-P01 in the following applications:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human Wnt3 Protein
INT4Proto-oncogene Int-4 homolog
wingless-type MMTV integration site family, member 3
WNT-3 proto-oncogene protein
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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