WB, ICC/IF, IHC, IHC-P, PEP-ELISAHost:
Applications: WB, IHC
Host: Mouse Monoclonal
Host: Rabbit Polyclonal
WB, ELISA, Func, PA, AP
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
|Product By Gene ID
- WNT-3 proto-oncogene protein
- proto-oncogene Wnt-3
- INT4Proto-oncogene Int-4 homolog
- wingless-type MMTV integration site family, member 3
Bioinformatics Tool for Wnt3
Discover related pathways, diseases and genes to Wnt3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.