Wnt-4 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: mFluor Violet 500 SE

Wnt-4 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Wnt-4
  Ser23-Arg351
  Accession # P56705
• Specificity: Detects human Wnt-4 in direct ELISAs. In direct ELISAs, approximately 10-15% cross-reactivity with recombinant human Wnt-3A and recombinant mouse Wnt-10B is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: WNT4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Wnt-4 Antibody [mFluor Violet 500 SE]

• protein Wnt-4
• SERKAL
• wingless-type MMTV integration site family, member 4
• Wnt4
• Wnt-4

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT4 is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and DAX1, a gene known to antagonize the testis-determining factor, play a concerted role in both the control of female development and the prevention of testes formation. WNT4 and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: WNT4