VE-Statin/EGFL7 Antibody

Western Blot: VE-Statin/EGFL7 Antibody [NBP2-44320] - Analysis of Heart (A), Kidney (B) and Lung (C) lysates (35ug protein in RIPA buffer).

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

VE-Statin/EGFL7 Antibody Summary

• Immunogen: Peptide with sequence C-HGDPVSESFVQR, from the internal region of the protein sequence according to NP_057299.1.
• Specificity: The immunizing peptide represents the N terminus of the mature protein. Reported variants represent identical protein: NP_057299.1, NP_958854.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: EGFL7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1 - 3 ug/ml
• Application Notes: Western blot: Approx 26-27kDa band observed in Human Heart, Kidney and Lung lysates (calculated MW of 29.6kDa according to NP_057299.1). The observed molecular weight corresponds to the mature form (calc. MW 27.1kDa without its 23aa signal peptide). Recommended concentration: 1-3ug/ml.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for VE-Statin/EGFL7 Antibody

• EGFL7
• EGF-like protein 7
• EGF-like-domain, multiple 7
• epidermal growth factor-like protein 7
• MEGF7
• MGC111117
• Multiple EGF-like domains protein 7
• Multiple epidermal growth factor-like domains protein 7
• NEU1 protein
• NOTCH4-like protein
• RP11-251M1.2
• Vascular endothelial statin
• VEStatin
• VE-Statin
• ZNEU1

Background

Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VE-Statin/EGFL7 Antibody (NBP2-44320)(1)

Publication using NBP2-44320

• Delfortrie S, Pinte S, Mattot V et al. Egfl7 promotes tumor escape from immunity by repressing endothelial cell activation. Cancer Res 2011-12-01 [PMID: 22037871]

Bioinformatics

• Gene Symbol: EGFL7
• Uniprot:
  • NP_057299.1(Human)