VE-Statin/EGFL7 Antibody (3G1) - Azide and BSA Free

Sandwich ELISA: VE-Statin/EGFL7 Antibody (3G1) [H00051162-M02] - Detection limit for recombinant GST tagged EGFL7 is approximately 3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 3G1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

VE-Statin/EGFL7 Antibody (3G1) - Azide and BSA Free Summary

• Immunogen: EGFL7 (AAH12377.1, 24 a.a. ~ 273 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. YRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDERSARRGGCPQRCINTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLLVHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS
• Localization: Secreted
• Specificity: EGFL7 - EGF-like-domain, multiple 7
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: EGFL7
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: Antibody reactive against recombinant protein on ELISA. GST alone used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for VE-Statin/EGFL7 Antibody (3G1) - Azide and BSA Free

• EGFL7
• EGF-like protein 7
• EGF-like-domain, multiple 7
• epidermal growth factor-like protein 7
• MEGF7
• MGC111117
• Multiple EGF-like domains protein 7
• Multiple epidermal growth factor-like domains protein 7
• NEU1 protein
• NOTCH4-like protein
• RP11-251M1.2
• Vascular endothelial statin
• VEStatin
• VE-Statin
• ZNEU1

Background

EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VE-Statin/EGFL7 Antibody (H00051162-M02)(1)

Publication using H00051162-M02

• Badiwala MV, Tumiati LC, Joseph JM et al. Epidermal Growth Factor-Like Domain 7 Suppresses Intercellular Adhesion Molecule 1 Expression in Response to Hypoxia/Reoxygenation Injury in Human Coronary Artery Endothelial Cells. Circulation. 2010-09-14 [PMID: 20837907]

Bioinformatics

• Gene Symbol: EGFL7
• Entrez:
  • 51162(Human)
• OMIM:
  • 608582(Human)
• Uniprot:
  • AAH12377(Human)