Vanilloid R-like 3/TRPV3 Antibody (S15/4) [Alexa Fluor® 750]

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC, IP, MA
• Clone: S15/4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

Vanilloid R-like 3/TRPV3 Antibody (S15/4) [Alexa Fluor® 750] Summary

• Immunogen: Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3
• Localization: Membrane
• Specificity: Detects approx 70 kDa.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRPV3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Microarray
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Vanilloid R-like 3/TRPV3 Antibody (S15/4) [Alexa Fluor® 750]

• transient receptor potential cation channel subfamily V member 3
• transient receptor potential cation channel, subfamily V, member 3
• TRPV3
• vanilloid receptor 3
• Vanilloid receptor-like 3
• vanilloid receptor-related osmotically activated channel protein
• Vanilloid R-like 3
• VanilloidR like 3
• VanilloidR-like3
• VRL3
• VRL-3

Background

Transient receptor potential (TRP) proteins are cation selective channels that function in processes as diverse as sensation and vasoregulation. TRPV3 is a receptor activated non selective calcium permeant cation channel that is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. TRPV3 is expressed in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain and is thermosensitive in the physiological range of temperatures between TRPM8 and TRPV1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRPV3