USP19 Antibody

Western Blot: USP19 Antibody [NB100-79829] - Detection of Human USP19/ZMYND9 on HeLa whole cell lysate using NB10-79827. USP19/ZMYND9 was also immunoprecipitated by rabbit anti-USP19/ZMYND9 antibody NB100-79828.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

USP19 Antibody Summary

• Description: Novus Biologicals Rabbit USP19 Antibody (NB100-79829) is a polyclonal antibody validated for use in WB and IP. Anti-USP19 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 900 and 950 of human ubiquitin specific peptidase 19 (zinc finger MYND domain-containing protein 9) using the numbering given in entry NP_006668.1 (GeneID 10869).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USP19
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for USP19 Antibody

• Deubiquitinating enzyme 19
• EC 3.1.2.15
• EC 3.4.19.12
• KIAA0891
• Ubiquitin Carboxyl-Terminal Hydrolase 19
• ubiquitin specific peptidase 19
• ubiquitin thioesterase 19
• Ubiquitin Thiolesterase 19
• Ubiquitin-specific-processing protease 19
• USP19
• Zinc finger MYND domain-containing protein 9
• ZMYND9
• ZMYND9ubiquitin specific protease 19

Background

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 19 (USP19) is a member of this family. USP19 is a 146 kDa protein that contains two CS domains and one MYND-type zinc finger.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for USP19 Antibody (NB100-79829)(2)

Publications using NB100-79829

• Mei Y, Hahn AA, Hu S, Yang X. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. J Biol Chem. 2011-08-17 [PMID: 21849505]
• Hassink GC, Zhao B, Sompallae R et al. The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates. EMBO Rep 2009-07-01 [PMID: 19465887]

Bioinformatics

• Gene Symbol: USP19
• Entrez:
  • 10869(Human)
• Uniprot:
  • O94966()