UGRP1/SCGB3A2 Antibody [Alexa Fluor® 488]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

UGRP1/SCGB3A2 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C
  Leu22-Leu139
  Accession # Q920H1
• Specificity: Detects mouse UGRP1/SCGB3A2 isoforms C and A in direct ELISAs and Western blots. It is also expected to recognize isoform B in direct ELISAs and Western blots. In Western blots, approximately 15% cross-reactivity with recombinant human UGRP1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for UGRP1/SCGB3A2 Antibody [Alexa Fluor® 488]

• LU103
• Pneumo secretory protein 1
• PnSP-1
• PNSP1secretoglobin family 3A member 2
• SCGB3A2
• secretoglobin, family 3A, member 2
• UGRP1
• UGRP1pnSP-1
• Uteroglobin-related protein 1

Background

UGRP-1, also known as secretoglobin family 3A member 2 (SCGB3A2) and HIN-2, is a secreted homodimeric protein that is highly expressed in epithelial cells of the airway. By alternative splicing events, three isoforms (A, B, C) that differ in their C-terminal regions, exist. UGRP-1 has been shown to bind MARCO (macrophage scavenger receptor with collagenous structure), which is expressed by alveolar macrophages. UGRP1 has been suggested to play a role in lung inflammation. Mature mouse UGRP1 isoform A shares 86% and 81% amino acid sequence identity with rat and human mature UGRP1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.