UCP4 Antibody

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Product Details

Summary
Reactivity NASpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
5.0 mg/ml

Order Details

UCP4 Antibody Summary

Immunogen
Synthetic peptide corresponding to the amino acids 271 - 283 of the native molecule conjugated to Keyhole limpet Haemocyanin. Peptide Sequence K-S-S-T-D-C-L-I-Q-A-V-Q-G
Specificity
UNCOUPLING PROTEIN 4
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC25A27
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Application Notes
In reduced blots on bovine brown adipose tissue homogenates, this antibody recognises specific bands at 34 & 44kD and other bands at 50 & 60 kD that can be blocked with KLH.
Publications
Read Publication using
NB100-66495 in the following applications:

  • WB
    1 publication

Reactivity Notes

Chemical

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
0.09% Sodium Azide
Concentration
5.0 mg/ml
Purity
Protein G purified

Alternate Names for UCP4 Antibody

  • FLJ33552
  • mitochondrial uncoupling protein 4
  • Solute carrier family 25 member 27
  • solute carrier family 25, member 27
  • UCP 4
  • UCP4uncoupling protein 4

Background

Mitochondrial uncoupling proteins (UCPs) create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. They may play a role in thermoregulatory heat production and metabolism in brain. They are found in adult and fetal brain and are present in most of the brain tissues, with low levels in spinal chord, corpus callosum and substantia nigra. They are specifically modulated by various environmental conditions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ELISA

Publications for UCP4 Antibody (NB100-66495)(1)

We have publications tested in 1 confirmed species: Insect (Rhodnius prolixus).

We have publications tested in 1 application: WB.


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(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SLC25A27
Entrez
Uniprot