Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
UBTF (NP_055048, 551 a.a. ~ 650 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYIS
Specificity
UBTF - upstream binding transcription factor, RNA polymerase I (2D8)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
UBTF
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for UBTF Antibody (2D8) - Azide and BSA Free
90-KDa Nucleolus Organizer Region Autoantigen
Autoantigen NOR-90
NOR-90
nucleolar transcription factor 1
UBF
UBF1
UBF-1
UBF2
UBFUBF-1
upstream binding transcription factor, RNA polymerase I
Upstream-binding factor 1
Background
Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
We have publications tested in 1 confirmed species: Human.
We have publications tested in 2 applications: ICC/IF, WB.
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ICC/IF
(1)
WB
(1)
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Showing Publication 1 - 1 of 1.
Publication using H00007343-M04
Applications
Species
Lum KKY Integrating Virology and Proteomics to Comprehend Mechanisms of Innate Immune Signaling During Herpesvirus Infection Thesis (WB, ICC/IF, Human)
WB, ICC/IF
Human
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