Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Po, Bv, Pm
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM]
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
7343 |
| Alternate Names |
- 90-KDa Nucleolus Organizer Region Autoantigen
- Autoantigen NOR-90
- NOR-90
- nucleolar transcription factor 1
- UBF
- UBF1
- UBF-1
- UBF2
- UBFUBF-1
- upstream binding transcription factor, RNA polymerase I
- Upstream-binding factor 1
|
