Ubiquilin 1 Antibody [FITC]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: FITC

Ubiquilin 1 Antibody [FITC] Summary

• Immunogen: E. coli-derived recombinant human Ubiquilin 1
  Arg546-Gly585
  Accession # Q9UMX0
• Specificity: Detects human Ubiquilin 1 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: UBQLN1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Ubiquilin 1 Antibody [FITC]

• DA41
• DA41FLJ90054
• DSK2
• hPLIC-1
• PLIC1
• PLIC-1
• PLIC-1UBQN
• Protein linking IAP with cytoskeleton 1
• Ubiquilin 1
• ubiquilin-1
• UBQLN1
• UBQN
• XDRP1

Background

Ubiquilin 1 encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBQLN1