Ubiquilin 1 Antibody (1C6-B7) - Azide and BSA Free

Western Blot: Ubiquilin 1 Antibody (1C6-B7) [H00029979-M02] - Analysis of UBQLN1 expression in transfected 293T cell line by UBQLN1 monoclonal antibody (M02), clone 1C6-B7. Lane 1: UBQLN1 transfected lysate (Predicted MW: 59.2 KDa). Lane 2: Non-transfected lysate.

Sandwich ELISA: Ubiquilin 1 Antibody (1C6-B7) [H00029979-M02] - Detection limit for recombinant GST tagged UBQLN1 is 0.03 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 1C6-B7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Ubiquilin 1 Antibody (1C6-B7) - Azide and BSA Free Summary

• Immunogen: UBQLN1 (AAH39294, 1 a.a. ~ 589 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAESGESGGPPGSQDSAAGAEGAGTPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNHDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTASGTSGQSTTAPNLVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLGALGSTGGSSGTNGSNATPSENTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQPS
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: UBQLN1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: This antibody is useful for ELISA, Western Blot

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Ubiquilin 1 Antibody (1C6-B7) - Azide and BSA Free

• DA41
• DA41FLJ90054
• DSK2
• hPLIC-1
• PLIC1
• PLIC-1
• PLIC-1UBQN
• Protein linking IAP with cytoskeleton 1
• Ubiquilin 1
• ubiquilin-1
• UBQLN1
• UBQN
• XDRP1

Background

This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Ubiquilin 1 Antibody (H00029979-M02)(1)

Publication using H00029979-M02

• Gerson JE, Linton H, Xing J, et al. Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins Scientific reports 2021-01-11 [PMID: 33431932] (WB, Human)

Bioinformatics

• Gene Symbol: UBQLN1
• Uniprot:
  • AAH39294(Human)