U1A Antibody

Western Blot: U1A Antibody [H00006626-D01P] - Analysis of SNRPA expression in mouse kidney.

Western Blot: U1A Antibody [H00006626-D01P] - Analysis of SNRPA expression in human kidney.

Western Blot: U1A Antibody [H00006626-D01P] - Analysis of SNRPA expression in transfected 293T cell line by SNRPA polyclonal antibody.Lane 1: SNRPA transfected lysate(31.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

U1A Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SNRPA (NP_004587.1, 1 a.a. - 282 a.a.) full-length human protein. MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK
• Specificity: SNRPA - small nuclear ribonucleoprotein polypeptide A,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SNRPA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for U1A Antibody

• Mud1
• small nuclear ribonucleoprotein polypeptide A
• U1 snRNP A
• U1 snRNP-specific protein A
• U1-AU1 small nuclear ribonucleoprotein A
• U1AU1 small nuclear RNP-specific A

Background

U1A binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and p

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for U1A Antibody (H00006626-D01P)(1)

Publication using H00006626-D01P

• Sun S, Ling SC, Qiu J et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nat Commun 2015-01-01 [PMID: 25625564] (WB)

Bioinformatics

• Gene Symbol: SNRPA
• Entrez:
  • 6626(Human)
• Uniprot:
  • NP_004587.1(Human)