TSPAN8/TM4SF3 Antibody (1E5)

Western Blot: TSPAN8/TM4SF3 Antibody (1E5) [H00007103-M02] - Analysis of TSPAN8 expression in transfected 293T cell line by TSPAN8 monoclonal antibody (M02), clone 1E5.Lane 1: TSPAN8 transfected lysate (Predicted MW: 26.1 KDa).Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: TSPAN8/TM4SF3 Antibody (1E5) [H00007103-M02] - Analysis of monoclonal antibody to TSPAN8 on 293 cell . Antibody concentration 10 ug/ml.

Western Blot: TSPAN8/TM4SF3 Antibody (1E5) [H00007103-M02] - detection against Immunogen (36.67 KDa) .

Western Blot: TSPAN8/TM4SF3 Antibody (1E5) [H00007103-M02] - 3 human pancreas cancer cell lines. Image from verified customer review.

Product Discontinued

TSPAN8/TM4SF3 Antibody (1E5) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: TSPAN8 (NP_004607, 110 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KSKSDRIVNETLYENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQRPCQSYNGKQVYKETCISFIKDFLAKN
• Specificity: TSPAN8 (1E5)
• Isotype: IgG3 Lambda
• Clonality: Monoclonal
• Host: Mouse
• Gene: TSPAN8
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TSPAN8/TM4SF3 Antibody (1E5)

• CO-029
• tetraspanin 8
• TM4SF3
• TM4SF3tspan-8
• Transmembrane 4 superfamily member 3tetraspanin-8
• TSPAN8
• Tspan-8
• Tumor-associated antigen CO-029

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TSPAN8/TM4SF3 Antibody (H00007103-M02)(1)

Publication using H00007103-M02

• Zhou Z, Ran YL, Hu H et al. TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression. Clin Exp Metastasis;25(5):537-48. 2008-01-01 [PMID: 18365756]

Review for TSPAN8/TM4SF3 Antibody (H00007103-M02) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Ming Lu WB Human 07/03/2014

Summary

• Application: Western Blot
• Sample Tested: 3 human pancreas cancer cell lines
• Species: Human
• Lot: D5031-1E5

Bioinformatics

• Gene Symbol: TSPAN8
• Entrez:
  • 7103(Human)
• OMIM:
  • 600769(Human)
• Uniprot:
  • NP_004607()