TRUSS Antibody - BSA Free

Western Blot: TRUSS Antibody [NBP2-20741] - Sample (30 ug of whole cell lysate) A: A549 7. 5% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

TRUSS Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit TRUSS Antibody - BSA Free (NBP2-20741) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human TRUSS. The exact sequence is proprietary.
• Marker: Myelinated Neurons Marker
• Predicted Species: Mouse (100%), Rat (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TRPC4AP
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 91 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (83%), Chicken (83%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for TRUSS Antibody - BSA Free

• C20orf188
• dJ756N5.2
• DKFZp586C1223
• DKFZP727M231
• Protein TAP1
• Protein TRUSS
• short transient receptor potential channel 4 associated protein
• short transient receptor potential channel 4-associated protein
• TNF-receptor ubiquitous scaffolding/signaling protein
• transient receptor potential cation channel, subfamily C, member 4 associatedprotein
• Trp4-associated protein
• Trpc4-associated protein
• TRRP4APchromosome 20 open reading frame 188
• TRUSS
• tumor necrosis factor receptor-associated ubiquitous scaffolding and signalingprotein

Background

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: TRPC4AP
• Uniprot:
  • Q8TEL6(Human)