TRPV6 Antibody

ELISA: TRPV6 Antibody [43470002]

Product Discontinued

TRPV6 Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human TRPV6.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TRPV6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for TRPV6 Antibody

• ABP/ZF
• calcium channel CaT1
• Calcium transport protein 1
• CaT1
• CATL
• CaT-L
• CaT-like
• ECAC2
• ECAC2caT-L
• epithelial apical membrane calcium transporter/channel CaT1
• Epithelial calcium channel 2Alu-binding protein with zinc finger domain
• HSA277909
• LP6728
• transient receptor potential cation channel subfamily V member 6
• transient receptor potential cation channel, subfamily V, member 6
• TRPV6
• ZFAB

Background

TRPV6 is a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine. It regulates calcium entry into the cell and is located in the apical brush border membrane of the intestinal enterocyte. Expression of TRPV6 appears to be vitamin D dependent as it is greatly reduced in animals that do not express the vitamin D receptor. Vitamin D treatment of colon cancer cells, Caco 2, also increases expression of TRPV6 gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TRPV6 Antibody (43470002)(2)

Publications using 43470002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: TRPV6
• Entrez:
  • 55503(Human)
• Uniprot:
  • Q9H1D0()