Epithelial calcium channel 2Alu-binding protein with zinc finger domain
transient receptor potential cation channel subfamily V member 6
transient receptor potential cation channel, subfamily V, member 6
TRPV6 is a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine. It regulates calcium entry into the cell and is located in the apical brush border membrane of the intestinal enterocyte. Expression of TRPV6 appears to be vitamin D dependent as it is greatly reduced in animals that do not express the vitamin D receptor. Vitamin D treatment of colon cancer cells, Caco 2, also increases expression of TRPV6 gene.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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