TRPV6 Products

Antibodies
TRPV6 Antibody
TRPV6 Antibody
NBP1-74138
Species: Hu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
TRPV6 Antibody
TRPV6 Antibody
43470002
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
TRPV6 Antibody
TRPV6 Antibody
NBP2-32372
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
TRPV6 Overexpression Lysate ( ...
TRPV6 Overexpression Lysate (Native)
NBL1-17345
Applications: WB
Proteins
TRPV6 Recombinant Protein Ant ...
TRPV6 Recombinant Protein Antigen
NBP2-32372PEP
Species: Hu
Applications: AC
Recombinant Human TRPV6 Prote ...
Recombinant Human TRPV6 Protein
H00055503-G01-10ug
Species: Hu
RNAi
TRPV6 RNAi
TRPV6 RNAi
H00055503-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Calcium-permeable channels, such as TRPV6, participate in neurotransmission, muscle contraction, and exocytosis by providing calcium as an intracellular second messenger. Depending on the tissue, transcellular calcium transport may be regulated by vitamin D, parathyroid hormone (PTH), or calcitonin (CALCA); FUNCTION: Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. SUBUNIT: Homotetramer and probably heterotetramer with TRPV5. Interacts with TRPV5. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with BSPRY. Interacts with calmodulin. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 55503
Alternate Names
  • TrpV6
  • LP6728
  • ECaC2
  • HSA277909
  • CaT-like
  • ABP/ZF
  • CaT-L
  • CATL
  • transient receptor potential cation channel subfamily V member 6
  • CAT1
  • epithelial apical membrane calcium transporter/channel CaT1
  • Calcium transport protein 1
  • calcium channel CaT1
  • CaT1
  • ECAC2caT-L
  • Epithelial calcium channel 2Alu-binding protein with zinc finger domain
  • ZFAB
  • transient receptor potential cation channel, subfamily V, member 6

Research Areas for TRPV6

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for TRPV6

Discover related pathways, diseases and genes to TRPV6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TRPV6 Blog Posts

Check out the latest blog posts on TRPV6.
Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...    Read more.
Read more TRPV6 related blogs.